TY  - GEN
AU  - Wang,Yan-Ting
AU  - Shi,Tian-Qi
AU  - Zhu,Hai-Liang
AU  - Liu,Chang-Hong
TI  - Synthesis, biological evaluation and molecular docking of benzimidazole grafted benzsulfamide-containing pyrazole ring derivatives as novel tubulin polymerization inhibitors
SN  - 1464-3391
PY  - 2019///1210
KW  - Animals
KW  - Antineoplastic Agents
KW  - chemical synthesis
KW  - Apoptosis
KW  - drug effects
KW  - Benzimidazoles
KW  - Cell Cycle Checkpoints
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Dose-Response Relationship, Drug
KW  - Drug Screening Assays, Antitumor
KW  - HEK293 Cells
KW  - Hepatocytes
KW  - Humans
KW  - Mice
KW  - Molecular Docking Simulation
KW  - Molecular Structure
KW  - Polymerization
KW  - Pyrazoles
KW  - chemistry
KW  - Structure-Activity Relationship
KW  - Sulfonamides
KW  - Tubulin
KW  - metabolism
KW  - Tubulin Modulators
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.bmc.2018.12.031
ER  -