TY - GEN AU - Campbell,Aideen M AU - Morris,Melanie AU - Gallagher,Rebecca AU - Boyd,Ruth AU - Carson,Hazel AU - Harkin,D Paul AU - Wielogorska,Ewa AU - Elliott,Christopher AU - Savage,Kienan I AU - McIntosh,Stuart A TI - Chemoprevention in BRCA1 mutation carriers (CIBRAC): protocol for an open allocation crossover feasibility trial assessing mechanisms of chemoprevention with goserelin and anastrozole versus tamoxifen and acceptability of treatment SN - 2044-6055 PY - 2019///1029 KW - Adult KW - Anastrozole KW - therapeutic use KW - Antineoplastic Agents, Hormonal KW - Breast Neoplasms KW - drug therapy KW - Chemoprevention KW - methods KW - Cross-Over Studies KW - Disease-Free Survival KW - Feasibility Studies KW - Female KW - Genetic Predisposition to Disease KW - epidemiology KW - Goserelin KW - Heterozygote KW - Humans KW - Mutation KW - Northern Ireland KW - Patient Acceptance of Health Care KW - statistics & numerical data KW - Patient Selection KW - Premenopause KW - physiology KW - Prognosis KW - Risk Assessment KW - Survival Rate KW - Tamoxifen KW - Treatment Outcome KW - Ubiquitin-Protein Ligases KW - genetics N1 - Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1136/bmjopen-2018-023115 ER -