Campbell, Aideen M

Chemoprevention in BRCA1 mutation carriers (CIBRAC): protocol for an open allocation crossover feasibility trial assessing mechanisms of chemoprevention with goserelin and anastrozole versus tamoxifen and acceptability of treatment. [electronic resource] - BMJ open 12 2018 - e023115 p. digital

Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't

2044-6055

10.1136/bmjopen-2018-023115 doi


Adult
Anastrozole--therapeutic use
Antineoplastic Agents, Hormonal--therapeutic use
Breast Neoplasms--drug therapy
Chemoprevention--methods
Cross-Over Studies
Disease-Free Survival
Feasibility Studies
Female
Genetic Predisposition to Disease--epidemiology
Goserelin--therapeutic use
Heterozygote
Humans
Mutation
Northern Ireland
Patient Acceptance of Health Care--statistics & numerical data
Patient Selection
Premenopause--physiology
Prognosis
Risk Assessment
Survival Rate
Tamoxifen--therapeutic use
Treatment Outcome
Ubiquitin-Protein Ligases--genetics