Predicting Patient Response to the Antiarrhythmic Mexiletine Based on Genetic Variation. [electronic resource]
- Circulation research 02 2019
- 539-552 p. digital
Publication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1524-4571
10.1161/CIRCRESAHA.118.314050 doi
Adolescent Adult Animals Anti-Arrhythmia Agents--pharmacology Female HEK293 Cells Humans Ion Channel Gating Long QT Syndrome--drug therapy Male Mexiletine--pharmacology Mutation, Missense NAV1.5 Voltage-Gated Sodium Channel--chemistry Pharmacogenomic Variants Sodium Channel Blockers--pharmacology Xenopus