TY  - GEN
AU  - Nguyen,Duy
AU  - Lemos,Clara
AU  - Wortmann,Lars
AU  - Eis,Knut
AU  - Holton,Simon J
AU  - Boemer,Ulf
AU  - Moosmayer,Dieter
AU  - Eberspaecher,Uwe
AU  - Weiske,Joerg
AU  - Lechner,Christian
AU  - Prechtl,Stefan
AU  - Suelzle,Detlev
AU  - Siegel,Franziska
AU  - Prinz,Florian
AU  - Lesche,Ralf
AU  - Nicke,Barbara
AU  - Nowak-Reppel,Katrin
AU  - Himmel,Herbert
AU  - Mumberg,Dominik
AU  - von Nussbaum,Franz
AU  - Nising,Carl F
AU  - Bauser,Marcus
AU  - Haegebarth,Andrea
TI  - Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2- d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5
SN  - 1520-4804
PY  - 2019///1017
KW  - Apoptosis
KW  - drug effects
KW  - Binding Sites
KW  - Cell Differentiation
KW  - Cell Line
KW  - Cell Proliferation
KW  - Crystallography, X-Ray
KW  - Drug Evaluation, Preclinical
KW  - Half-Life
KW  - Humans
KW  - Mitogen-Activated Protein Kinase 7
KW  - antagonists & inhibitors
KW  - Molecular Docking Simulation
KW  - Protein Kinase Inhibitors
KW  - chemistry
KW  - Protein Structure, Tertiary
KW  - Pyridines
KW  - Pyrimidines
KW  - Signal Transduction
KW  - Structure-Activity Relationship
KW  - Transcription, Genetic
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/acs.jmedchem.8b01606
ER  -