TY  - GEN
AU  - Yao,Zhan
AU  - Gao,Yijun
AU  - Su,Wenjing
AU  - Yaeger,Rona
AU  - Tao,Jessica
AU  - Na,Na
AU  - Zhang,Ying
AU  - Zhang,Chao
AU  - Rymar,Andrey
AU  - Tao,Anthony
AU  - Timaul,Neilawattie M
AU  - Mcgriskin,Rory
AU  - Outmezguine,Nathaniel A
AU  - Zhao,HuiYong
AU  - Chang,Qing
AU  - Qeriqi,Besnik
AU  - Barbacid,Mariano
AU  - de Stanchina,Elisa
AU  - Hyman,David M
AU  - Bollag,Gideon
AU  - Rosen,Neal
TI  - RAF inhibitor PLX8394 selectively disrupts BRAF dimers and RAS-independent BRAF-mutant-driven signaling
SN  - 1546-170X
PY  - 2019///0510
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - drug effects
KW  - Extracellular Signal-Regulated MAP Kinases
KW  - metabolism
KW  - Heterocyclic Compounds, 2-Ring
KW  - pharmacology
KW  - Humans
KW  - Mutation
KW  - genetics
KW  - Phosphorylation
KW  - Protein Multimerization
KW  - Proto-Oncogene Proteins B-raf
KW  - Signal Transduction
KW  - Sulfonamides
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/s41591-018-0274-5
ER  -