Yao, Zhan <br/><br/>
RAF inhibitor PLX8394 selectively disrupts BRAF dimers and RAS-independent BRAF-mutant-driven signaling.  [electronic resource] 

 -  Nature medicine  02 2019 
 - 284-291 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1546-170X 
<br/><br/><label>Standard No.: </label>10.1038/s41591-018-0274-5  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Extracellular Signal-Regulated MAP Kinases--metabolism<br/>Heterocyclic Compounds, 2-Ring--pharmacology<br/>Humans<br/>Mutation--genetics<br/>Phosphorylation--drug effects<br/>Protein Multimerization<br/>Proto-Oncogene Proteins B-raf--genetics<br/>Signal Transduction<br/>Sulfonamides--pharmacology