TY - GEN AU - Pohl,Kerstin AU - Nichols,David P AU - Taylor-Cousar,Jennifer L AU - Saavedra,Milene T AU - Strand,Matthew J AU - Nick,Jerry A AU - Bratcher,Preston E TI - Corticosteroid use and increased CXCR2 levels on leukocytes are associated with lumacaftor/ivacaftor discontinuation in cystic fibrosis patients homozygous for the F508del CFTR mutation SN - 1932-6203 PY - 2019///0514 KW - Adrenal Cortex Hormones KW - therapeutic use KW - Adult KW - Aminophenols KW - adverse effects KW - Aminopyridines KW - Benzodioxoles KW - Cystic Fibrosis KW - drug therapy KW - Cystic Fibrosis Transmembrane Conductance Regulator KW - genetics KW - Drug Combinations KW - Female KW - Forced Expiratory Volume KW - Gene Deletion KW - Homozygote KW - Humans KW - Leukocytes KW - metabolism KW - Logistic Models KW - Male KW - Medication Adherence KW - Quinolones KW - Receptors, Interleukin-8B KW - Tetraspanin 30 N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0209026 ER -