TY - GEN AU - Chen,Lindi AU - Pastorino,Fabio AU - Berry,Philip AU - Bonner,Jennifer AU - Kirk,Calum AU - Wood,Katrina M AU - Thomas,Huw D AU - Zhao,Yan AU - Daga,Antonio AU - Veal,Gareth J AU - Lunec,John AU - Newell,David R AU - Ponzoni,Mirco AU - Tweddle,Deborah A TI - Preclinical evaluation of the first intravenous small molecule MDM2 antagonist alone and in combination with temozolomide in neuroblastoma SN - 1097-0215 PY - 2019///1008 KW - Animals KW - Antineoplastic Combined Chemotherapy Protocols KW - pharmacology KW - Drug Screening Assays, Antitumor KW - Drug Synergism KW - Humans KW - Mice KW - Neuroblastoma KW - drug therapy KW - Prodrugs KW - pharmacokinetics KW - Proto-Oncogene Proteins c-mdm2 KW - antagonists & inhibitors KW - Pyrrolidines KW - Random Allocation KW - Temozolomide KW - administration & dosage KW - Tumor Suppressor Protein p53 KW - genetics KW - Xenograft Model Antitumor Assays KW - para-Aminobenzoates N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1002/ijc.32058 ER -