Li, Wenlong <br/><br/>
Discovery of Novel Quinoline-Chalcone Derivatives as Potent Antitumor Agents with Microtubule Polymerization Inhibitory Activity.  [electronic resource] 

 -  Journal of medicinal chemistry  01 2019 
 - 993-1013 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/acs.jmedchem.8b01755  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--chemistry<br/>Apoptosis--drug effects<br/>Binding Sites<br/>Cell Line, Tumor<br/>Chalcones--chemistry<br/>Drug Design<br/>G2 Phase Cell Cycle Checkpoints--drug effects<br/>Humans<br/>Liver Neoplasms--drug therapy<br/>Mice<br/>Mitochondria--drug effects<br/>Molecular Docking Simulation<br/>Oxidative Stress--drug effects<br/>Proto-Oncogene Proteins c-bcl-2--metabolism<br/>Quinolines--chemistry<br/>Structure-Activity Relationship<br/>Tubulin--chemistry<br/>Tubulin Modulators--chemistry