TY  - GEN
AU  - Coskun,Tamer
AU  - Sloop,Kyle W
AU  - Loghin,Corina
AU  - Alsina-Fernandez,Jorge
AU  - Urva,Shweta
AU  - Bokvist,Krister B
AU  - Cui,Xuewei
AU  - Briere,Daniel A
AU  - Cabrera,Over
AU  - Roell,William C
AU  - Kuchibhotla,Uma
AU  - Moyers,Julie S
AU  - Benson,Charles T
AU  - Gimeno,Ruth E
AU  - D'Alessio,David A
AU  - Haupt,Axel
TI  - LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept
SN  - 2212-8778
PY  - 2019///0904
KW  - Adult
KW  - Animals
KW  - Appetite
KW  - drug effects
KW  - Blood Glucose
KW  - metabolism
KW  - Body Weight
KW  - Diabetes Mellitus, Type 2
KW  - drug therapy
KW  - Diarrhea
KW  - etiology
KW  - Female
KW  - Gastric Inhibitory Polypeptide
KW  - adverse effects
KW  - Humans
KW  - Hypoglycemic Agents
KW  - Incretins
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Middle Aged
KW  - Receptors, Gastrointestinal Hormone
KW  - agonists
KW  - Vomiting
KW  - Tirzepatide
KW  - Glucagon-Like Peptide-1 Receptor Agonists
N1  - Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.molmet.2018.09.009
ER  -