Coskun, Tamer

LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept. [electronic resource] - Molecular metabolism 12 2018 - 3-14 p. digital

Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

2212-8778

10.1016/j.molmet.2018.09.009 doi


Adult
Animals
Appetite--drug effects
Blood Glucose--metabolism
Body Weight
Diabetes Mellitus, Type 2--drug therapy
Diarrhea--etiology
Female
Gastric Inhibitory Polypeptide--adverse effects
Humans
Hypoglycemic Agents--adverse effects
Incretins--adverse effects
Male
Mice
Mice, Inbred C57BL
Middle Aged
Receptors, Gastrointestinal Hormone--agonists
Vomiting--etiology
Tirzepatide
Glucagon-Like Peptide-1 Receptor Agonists