TY  - GEN
AU  - Chen,Ke
AU  - Huang,Liuliu
AU  - Shen,Bin
TI  - Rational cyclization-based minimization of entropy penalty upon the binding of Nrf2-derived linear peptides to Keap1: A new strategy to improve therapeutic peptide activity against sepsis
SN  - 1873-4200
PY  - 2019///0219
KW  - Animals
KW  - Cyclization
KW  - Drug Design
KW  - Entropy
KW  - Humans
KW  - Kelch-Like ECH-Associated Protein 1
KW  - Models, Theoretical
KW  - NF-E2-Related Factor 2
KW  - chemistry
KW  - Peptides
KW  - Protein Binding
KW  - Protein Conformation
KW  - Sepsis
KW  - drug therapy
KW  - Thermodynamics
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1016/j.bpc.2018.11.002
ER  -