Chen, Ke <br/><br/>
Rational cyclization-based minimization of entropy penalty upon the binding of Nrf2-derived linear peptides to Keap1: A new strategy to improve therapeutic peptide activity against sepsis.  [electronic resource] 

 -  Biophysical chemistry  01 2019 
 - 22-28 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1873-4200 
<br/><br/><label>Standard No.: </label>10.1016/j.bpc.2018.11.002  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Cyclization<br/>Drug Design<br/>Entropy<br/>Humans<br/>Kelch-Like ECH-Associated Protein 1<br/>Models, Theoretical<br/>NF-E2-Related Factor 2--chemistry<br/>Peptides--chemistry<br/>Protein Binding<br/>Protein Conformation<br/>Sepsis--drug therapy<br/>Thermodynamics