TY - GEN AU - Yu,Qin AU - Qu,Kun AU - Modis,Yorgo TI - Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis SN - 1097-4164 PY - 2019///0528 KW - Adenosine Triphosphate KW - metabolism KW - Cryoelectron Microscopy KW - HEK293 Cells KW - Humans KW - Hydrolysis KW - Hydrophobic and Hydrophilic Interactions KW - Interferon-Induced Helicase, IFIH1 KW - genetics KW - Interferon-beta KW - Molecular Docking Simulation KW - Mutation KW - Nucleic Acid Conformation KW - Protein Conformation KW - RNA, Double-Stranded KW - Signal Transduction KW - Structure-Activity Relationship N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media UR - https://doi.org/10.1016/j.molcel.2018.10.012 ER -