TY - GEN AU - Villahoz,Silvia AU - Yunes-Leites,Paula Sofía AU - Méndez-Barbero,Nerea AU - Urso,Katia AU - Bonzon-Kulichenko,Elena AU - Ortega,Sagrario AU - Nistal,J Francisco AU - Vazquez,Jesus AU - Offermanns,Stefan AU - Redondo,Juan Miguel AU - Campanero,Miguel R TI - Conditional deletion of Rcan1 predisposes to hypertension-mediated intramural hematoma and subsequent aneurysm and aortic rupture SN - 2041-1723 PY - 2018///1219 KW - Aortic Dissection KW - genetics KW - Animals KW - Antihypertensive Agents KW - pharmacology KW - Aorta KW - drug effects KW - Aortic Rupture KW - Calcium-Binding Proteins KW - Disease Models, Animal KW - Endothelial Cells KW - Gene Deletion KW - Gene Expression Regulation KW - Genetic Predisposition to Disease KW - Glycogen Synthase Kinase 3 beta KW - antagonists & inhibitors KW - Hematoma KW - Humans KW - Hypertension KW - drug therapy KW - Intracellular Signaling Peptides and Proteins KW - deficiency KW - Male KW - Mice KW - Mice, Knockout KW - Muscle Proteins KW - Myocytes, Smooth Muscle KW - Primary Cell Culture KW - Protein Isoforms KW - Protein Kinase Inhibitors KW - rho-Associated Kinases N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/s41467-018-07071-7 ER -