TY - GEN AU - Mariotti,Fabrizia AU - Govoni,Mirco AU - Lucci,Germano AU - Santoro,Debora AU - Nandeuil,Marie Anna TI - Safety, tolerability, and pharmacokinetics of single and repeat ascending doses of CHF6001, a novel inhaled phosphodiesterase-4 inhibitor: two randomized trials in healthy volunteers SN - 1178-2005 PY - 2019///0307 KW - Administration, Inhalation KW - Adult KW - Area Under Curve KW - Biological Availability KW - Dose-Response Relationship, Drug KW - Double-Blind Method KW - Drug Monitoring KW - methods KW - Dry Powder Inhalers KW - Female KW - Healthy Volunteers KW - Humans KW - Male KW - Middle Aged KW - Phosphodiesterase 4 Inhibitors KW - administration & dosage KW - Pulmonary Disease, Chronic Obstructive KW - drug therapy KW - Sulfonamides KW - para-Aminobenzoates N1 - Publication Type: Journal Article; Randomized Controlled Trial UR - https://doi.org/10.2147/COPD.S174156 ER -