Suryadevara, Carter M

Preventing Lck Activation in CAR T Cells Confers Treg Resistance but Requires 4-1BB Signaling for Them to Persist and Treat Solid Tumors in Nonlymphodepleted Hosts. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research 01 2019 - 358-368 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1557-3265

10.1158/1078-0432.CCR-18-1211 doi


Animals
CD28 Antigens--genetics
Heterografts
Humans
Immunotherapy, Adoptive
Interleukin-2--genetics
Mice
Neoplasms--immunology
Receptors, Chimeric Antigen--immunology
Signal Transduction
T-Lymphocytes, Regulatory--immunology
Tumor Necrosis Factor Receptor Superfamily, Member 9--genetics