TY  - GEN
AU  - Zeng,Mei
AU  - Kwiatkowski,Nicholas P
AU  - Zhang,Tinghu
AU  - Nabet,Behnam
AU  - Xu,Mousheng
AU  - Liang,Yanke
AU  - Quan,Chunshan
AU  - Wang,Jinhua
AU  - Hao,Mingfeng
AU  - Palakurthi,Sangeetha
AU  - Zhou,Shan
AU  - Zeng,Qing
AU  - Kirschmeier,Paul T
AU  - Meghani,Khyati
AU  - Leggett,Alan L
AU  - Qi,Jun
AU  - Shapiro,Geoffrey I
AU  - Liu,Joyce F
AU  - Matulonis,Ursula A
AU  - Lin,Charles Y
AU  - Konstantinopoulos,Panagiotis A
AU  - Gray,Nathanael S
TI  - Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13
SN  - 2050-084X
PY  - 2019///0311
KW  - Animals
KW  - Antineoplastic Agents
KW  - administration & dosage
KW  - CDC2 Protein Kinase
KW  - antagonists & inhibitors
KW  - Cell Line, Tumor
KW  - Cyclin-Dependent Kinases
KW  - Disease Models, Animal
KW  - Down-Regulation
KW  - Enzyme Inhibitors
KW  - Female
KW  - Heterografts
KW  - Humans
KW  - Mice, SCID
KW  - Neoplasm Transplantation
KW  - Ovarian Neoplasms
KW  - drug therapy
KW  - Phenylenediamines
KW  - Proto-Oncogene Proteins c-myc
KW  - biosynthesis
KW  - Pyrimidines
KW  - Treatment Outcome
KW  - Cyclin-Dependent Kinase-Activating Kinase
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.7554/eLife.39030
ER  -