TY - GEN AU - Stafford,James M AU - Lee,Chul-Hwan AU - Voigt,Philipp AU - Descostes,Nicolas AU - SaldaƱa-Meyer,Ricardo AU - Yu,Jia-Ray AU - Leroy,Gary AU - Oksuz,Ozgur AU - Chapman,Jessica R AU - Suarez,Fernando AU - Modrek,Aram S AU - Bayin,N Sumru AU - Placantonakis,Dimitris G AU - Karajannis,Matthias A AU - Snuderl,Matija AU - Ueberheide,Beatrix AU - Reinberg,Danny TI - Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma SN - 2375-2548 PY - 2019///0930 KW - Animals KW - Brain Stem Neoplasms KW - genetics KW - Cells, Cultured KW - Child KW - Chromatin KW - chemistry KW - Disease Models, Animal KW - Embryonic Stem Cells KW - metabolism KW - Glioma KW - Histones KW - Humans KW - Lysine KW - Mice KW - Polycomb Repressive Complex 2 KW - antagonists & inhibitors N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1126/sciadv.aau5935 ER -