TY  - GEN
AU  - Naylor,Matthew R
AU  - Ly,Andrew M
AU  - Handford,Mason J
AU  - Ramos,Daniel P
AU  - Pye,Cameron R
AU  - Furukawa,Akihiro
AU  - Klein,Victoria G
AU  - Noland,Ryan P
AU  - Edmondson,Quinn
AU  - Turmon,Alexandra C
AU  - Hewitt,William M
AU  - Schwochert,Joshua
AU  - Townsend,Chad E
AU  - Kelly,Colin N
AU  - Blanco,Maria-Jesus
AU  - Lokey,R Scott
TI  - Lipophilic Permeability Efficiency Reconciles the Opposing Roles of Lipophilicity in Membrane Permeability and Aqueous Solubility
SN  - 1520-4804
PY  - 2019///1028
KW  - 1-Octanol
KW  - chemistry
KW  - Cell Membrane Permeability
KW  - drug effects
KW  - Cyclosporins
KW  - Hydrogen Bonding
KW  - Hydrophobic and Hydrophilic Interactions
KW  - Peptides
KW  - Peptides, Cyclic
KW  - Pharmaceutical Preparations
KW  - Small Molecule Libraries
KW  - Solubility
KW  - Structure-Activity Relationship
KW  - Water
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/acs.jmedchem.8b01259
ER  -