TY - GEN AU - Xie,Xiaomeng AU - Liu,Kangdong AU - Liu,Feifei AU - Chen,Hanyong AU - Wang,Xiangyu AU - Zu,Xueyin AU - Ma,Xiaoli AU - Wang,Ting AU - Wu,Qiong AU - Zheng,Yan AU - Bode,Ann M AU - Dong,Zigang AU - Kim,Dong Joon TI - Gossypetin is a novel MKK3 and MKK6 inhibitor that suppresses esophageal cancer growth in vitro and in vivo SN - 1872-7980 PY - 2019///1104 KW - Animals KW - Antineoplastic Agents KW - chemistry KW - Apoptosis KW - drug effects KW - Apoptosis Regulatory Proteins KW - metabolism KW - Binding Sites KW - Cell Line, Tumor KW - Cell Proliferation KW - Esophageal Neoplasms KW - drug therapy KW - Esophageal Squamous Cell Carcinoma KW - Female KW - Flavonoids KW - G2 Phase Cell Cycle Checkpoints KW - Humans KW - MAP Kinase Kinase 3 KW - antagonists & inhibitors KW - MAP Kinase Kinase 6 KW - Mice, SCID KW - Molecular Docking Simulation KW - Protein Conformation KW - Protein Kinase Inhibitors KW - Signal Transduction KW - Tumor Burden KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.canlet.2018.10.016 ER -