Xie, Xiaomeng <br/><br/>
Gossypetin is a novel MKK3 and MKK6 inhibitor that suppresses esophageal cancer growth in vitro and in vivo.  [electronic resource] 

 -  Cancer letters  02 2019 
 - 126-136 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1872-7980 
<br/><br/><label>Standard No.: </label>10.1016/j.canlet.2018.10.016  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--chemistry<br/>Apoptosis--drug effects<br/>Apoptosis Regulatory Proteins--metabolism<br/>Binding Sites<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Esophageal Neoplasms--drug therapy<br/>Esophageal Squamous Cell Carcinoma--drug therapy<br/>Female<br/>Flavonoids--chemistry<br/>G2 Phase Cell Cycle Checkpoints--drug effects<br/>Humans<br/>MAP Kinase Kinase 3--antagonists & inhibitors<br/>MAP Kinase Kinase 6--antagonists & inhibitors<br/>Mice, SCID<br/>Molecular Docking Simulation<br/>Protein Conformation<br/>Protein Kinase Inhibitors--chemistry<br/>Signal Transduction--drug effects<br/>Tumor Burden--drug effects<br/>Xenograft Model Antitumor Assays