TY - GEN AU - Kam,Tae-In AU - Mao,Xiaobo AU - Park,Hyejin AU - Chou,Shih-Ching AU - Karuppagounder,Senthilkumar S AU - Umanah,George Essien AU - Yun,Seung Pil AU - Brahmachari,Saurav AU - Panicker,Nikhil AU - Chen,Rong AU - Andrabi,Shaida A AU - Qi,Chen AU - Poirier,Guy G AU - Pletnikova,Olga AU - Troncoso,Juan C AU - Bekris,Lynn M AU - Leverenz,James B AU - Pantelyat,Alexander AU - Ko,Han Seok AU - Rosenthal,Liana S AU - Dawson,Ted M AU - Dawson,Valina L TI - Poly(ADP-ribose) drives pathologic α-synuclein neurodegeneration in Parkinson's disease SN - 1095-9203 PY - 2018///1211 KW - Animals KW - Benzimidazoles KW - pharmacology KW - Brain KW - metabolism KW - Cell Death KW - Dopaminergic Neurons KW - Enzyme Activation KW - Gene Knockout Techniques KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Nitric Oxide KW - Parkinson Disease KW - Poly (ADP-Ribose) Polymerase-1 KW - antagonists & inhibitors KW - Poly Adenosine Diphosphate Ribose KW - Poly(ADP-ribose) Polymerase Inhibitors KW - Recombinant Proteins KW - genetics KW - alpha-Synuclein N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1126/science.aat8407 ER -