TY - GEN AU - O'Connor,Gemma AU - Krishnan,Nitya AU - Fagan-Murphy,Aidan AU - Cassidy,Joseph AU - O'Leary,Seonadh AU - Robertson,Brian D AU - Keane,Joseph AU - O'Sullivan,Mary P AU - Cryan,Sally-Ann TI - Inhalable poly(lactic-co-glycolic acid) (PLGA) microparticles encapsulating all-trans-Retinoic acid (ATRA) as a host-directed, adjunctive treatment for Mycobacterium tuberculosis infection SN - 1873-3441 PY - 2019///0422 KW - Administration, Inhalation KW - Animals KW - Antitubercular Agents KW - administration & dosage KW - Delayed-Action Preparations KW - Disease Models, Animal KW - Drug Carriers KW - chemistry KW - Drug Compounding KW - methods KW - Drug Liberation KW - Female KW - Humans KW - Macrophages, Alveolar KW - drug effects KW - Mice KW - Mice, Inbred BALB C KW - Mycobacterium tuberculosis KW - Particle Size KW - Polylactic Acid-Polyglycolic Acid Copolymer KW - Pulmonary Alveoli KW - THP-1 Cells KW - Treatment Outcome KW - Tretinoin KW - Tuberculosis, Pulmonary KW - drug therapy N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.ejpb.2018.10.020 ER -