Miller, N E

Mechanism-based inactivation of the major beta-naphthoflavone-inducible isozyme of rat liver cytochrome P-450 by the chloramphenicol analog N-(2-p-nitrophenethyl)dichloroacetamide. [electronic resource] - Drug metabolism and disposition: the biological fate of chemicals - 846-51 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0090-9556


Acetamides--pharmacology
Animals
Benzoflavones--pharmacology
Chloramphenicol--analogs & derivatives
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System--biosynthesis
Enzyme Induction--drug effects
Flavonoids--pharmacology
In Vitro Techniques
Isoenzymes--antagonists & inhibitors
Male
Microsomes, Liver--drug effects
Mixed Function Oxygenases--metabolism
NADPH-Ferrihemoprotein Reductase--metabolism
Oxidation-Reduction
Rats
Rats, Inbred Strains
beta-Naphthoflavone