TY  - GEN
AU  - Huang,Zhimin
AU  - Zhao,Junxing
AU  - Deng,Wei
AU  - Chen,Yingyi
AU  - Shang,Jialin
AU  - Song,Kun
AU  - Zhang,Lu
AU  - Wang,Chengxiang
AU  - Lu,Shaoyong
AU  - Yang,Xiuyan
AU  - He,Bin
AU  - Min,Jinrong
AU  - Hu,Hao
AU  - Tan,Minjia
AU  - Xu,Jianrong
AU  - Zhang,Qiufen
AU  - Zhong,Jie
AU  - Sun,Xiaoxiang
AU  - Mao,Zhiyong
AU  - Lin,Houwen
AU  - Xiao,Mingzhe
AU  - Chin,Y Eugene
AU  - Jiang,Hualiang
AU  - Xu,Ying
AU  - Chen,Guoqiang
AU  - Zhang,Jian
TI  - Identification of a cellularly active SIRT6 allosteric activator
SN  - 1552-4469
PY  - 2019///0508
KW  - Allosteric Regulation
KW  - Allosteric Site
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Benzoates
KW  - Carcinoma, Hepatocellular
KW  - drug therapy
KW  - Cell Line
KW  - Cell Line, Tumor
KW  - Crystallography, X-Ray
KW  - Female
KW  - High-Throughput Screening Assays
KW  - methods
KW  - Humans
KW  - Liver Neoplasms
KW  - Mice, Inbred BALB C
KW  - Molecular Dynamics Simulation
KW  - Molecular Targeted Therapy
KW  - Sirtuins
KW  - chemistry
KW  - Sulfur Compounds
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/s41589-018-0150-0
ER  -