Luffer-Atlas, Debra

PDGFRα monoclonal antibody: Assessment of embryo-fetal toxicity and time-dependent placental transfer of a murine surrogate antibody of olaratumab in mice. [electronic resource] - Birth defects research 11 2018 - 1358-1371 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2472-1727

10.1002/bdr2.1403 doi


Animals
Antibodies, Monoclonal--metabolism
Dose-Response Relationship, Drug
Embryo, Mammalian
Female
Fetal Development--drug effects
Fetus
Maternal Exposure--adverse effects
Mice
Mice, Inbred Strains
No-Observed-Adverse-Effect Level
Organogenesis
Pilot Projects
Placenta
Pregnancy
Receptor, Platelet-Derived Growth Factor alpha--immunology
Toxicity Tests--methods