TY  - GEN
AU  - Pereira,Adriana S A
AU  - Amaral,Murilo S
AU  - Vasconcelos,Elton J R
AU  - Pires,David S
AU  - Asif,Huma
AU  - daSilva,Lucas F
AU  - Morales-Vicente,David A
AU  - Carneiro,Vitor C
AU  - Angeli,Claudia B
AU  - Palmisano,Giuseppe
AU  - Fantappie,Marcelo R
AU  - Pierce,Raymond J
AU  - Setubal,João C
AU  - Verjovski-Almeida,Sergio
TI  - Inhibition of histone methyltransferase EZH2 in Schistosoma mansoni in vitro by GSK343 reduces egg laying and decreases the expression of genes implicated in DNA replication and noncoding RNA metabolism
SN  - 1935-2735
PY  - 2019///0109
KW  - Animals
KW  - DNA Replication
KW  - drug effects
KW  - Enhancer of Zeste Homolog 2 Protein
KW  - antagonists & inhibitors
KW  - Enzyme Inhibitors
KW  - pharmacology
KW  - Female
KW  - Gene Expression Regulation
KW  - Indazoles
KW  - Locomotion
KW  - Male
KW  - Metabolic Networks and Pathways
KW  - Microscopy, Electron, Scanning
KW  - Oviposition
KW  - Pyridones
KW  - RNA, Untranslated
KW  - metabolism
KW  - Schistosoma mansoni
KW  - Survival Analysis
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pntd.0006873
ER  -