TY  - GEN
AU  - Fukudo,Shin
AU  - Miwa,Hiroto
AU  - Nakajima,Atsushi
AU  - Kinoshita,Yoshikazu
AU  - Kosako,Masanori
AU  - Hayashi,Kenta
AU  - Akiho,Hiraku
AU  - Kuroishi,Kentaro
AU  - Johnston,Jeffrey M
AU  - Currie,Mark
AU  - Ohkusa,Toshifumi
TI  - High-dose linaclotide is effective and safe in patients with chronic constipation: A phase III randomized, double-blind, placebo-controlled study with a long-term open-label extension study in Japan
SN  - 1365-2982
PY  - 2020///0120
KW  - Adult
KW  - Aged
KW  - Chronic Disease
KW  - Constipation
KW  - drug therapy
KW  - Double-Blind Method
KW  - Female
KW  - Gastrointestinal Agents
KW  - therapeutic use
KW  - Guanylyl Cyclase C Agonists
KW  - Humans
KW  - Japan
KW  - Male
KW  - Middle Aged
KW  - Peptides
N1  - Publication Type: Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1111/nmo.13487
ER  -