Zhang, Keqiang

Targeting histone methyltransferase G9a inhibits growth and Wnt signaling pathway by epigenetically regulating HP1α and APC2 gene expression in non-small cell lung cancer. [electronic resource] - Molecular cancer 10 2018 - 153 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1476-4598

10.1186/s12943-018-0896-8 doi


Animals
Apoptosis
Carcinoma, Non-Small-Cell Lung--genetics
Cell Cycle Checkpoints
Cell Line, Tumor
Cell Movement
Cell Proliferation
Chromobox Protein Homolog 5
Chromosomal Proteins, Non-Histone--genetics
Cytoskeletal Proteins--genetics
DNA Methylation
Disease Models, Animal
Epigenesis, Genetic
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Histocompatibility Antigens--genetics
Histone-Lysine N-Methyltransferase--genetics
Humans
Lung Neoplasms--genetics
Mice
Quinazolines--pharmacology
Wnt Signaling Pathway
Xenograft Model Antitumor Assays