Andrade, Jason G A randomized clinical trial of early invasive intervention for atrial fibrillation (EARLY-AF) - methods and rationale. [electronic resource] - American heart journal 12 2018 - 94-104 p. digital Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't ISSN: 1097-6744 Standard No.: 10.1016/j.ahj.2018.05.020 doi Subjects--Topical Terms: Anti-Arrhythmia Agents--therapeutic useAtrial Fibrillation--physiopathologyCardiac Catheterization--methodsCryosurgery--methodsFemaleFollow-Up StudiesHeart Conduction System--physiopathologyHumansMaleMiddle AgedProspective StudiesPulmonary Veins--surgeryQuality of LifeSingle-Blind MethodTime FactorsTreatment Outcome