TY  - GEN
AU  - Chen,Yuehong
AU  - Jian,Jinlong
AU  - Hettinghouse,Aubryanna
AU  - Zhao,Xueheng
AU  - Setchell,Kenneth D R
AU  - Sun,Ying
AU  - Liu,Chuan-Ju
TI  - Progranulin associates with hexosaminidase A and ameliorates GM2 ganglioside accumulation and lysosomal storage in Tay-Sachs disease
SN  - 1432-1440
PY  - 2019///1105
KW  - Animals
KW  - Brain
KW  - metabolism
KW  - Disease Models, Animal
KW  - Fibroblasts
KW  - drug effects
KW  - Gangliosides
KW  - HEK293 Cells
KW  - Hexosaminidase A
KW  - Humans
KW  - Lysosomes
KW  - Mice
KW  - Mice, Knockout
KW  - Progranulins
KW  - genetics
KW  - RAW 264.7 Cells
KW  - Recombinant Proteins
KW  - pharmacology
KW  - Tay-Sachs Disease
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1007/s00109-018-1703-0
ER  -