Chen, Yuehong <br/><br/>
Progranulin associates with hexosaminidase A and ameliorates GM2 ganglioside accumulation and lysosomal storage in Tay-Sachs disease.  [electronic resource] 

 -  Journal of molecular medicine (Berlin, Germany)  12 2018 
 - 1359-1373 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1432-1440 
<br/><br/><label>Standard No.: </label>10.1007/s00109-018-1703-0  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Brain--metabolism<br/>Disease Models, Animal<br/>Fibroblasts--drug effects<br/>Gangliosides--metabolism<br/>HEK293 Cells<br/>Hexosaminidase A--metabolism<br/>Humans<br/>Lysosomes--metabolism<br/>Mice<br/>Mice, Knockout<br/>Progranulins--genetics<br/>RAW 264.7 Cells<br/>Recombinant Proteins--pharmacology<br/>Tay-Sachs Disease--metabolism