Lazzarotto, Cicera R <br/><br/>
Defining CRISPR-Cas9 genome-wide nuclease activities with CIRCLE-seq.  [electronic resource] 

 -  Nature protocols  Nov 2018 
 - 2615-2642 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1750-2799 
<br/><br/><label>Standard No.: </label>10.1038/s41596-018-0055-0  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>CRISPR-Associated Protein 9--genetics<br/>CRISPR-Cas Systems<br/>Cell Line, Tumor<br/>Clustered Regularly Interspaced Short Palindromic Repeats<br/>DNA, Circular--genetics<br/>Gene Editing--methods<br/>Gene Library<br/>Genome, Human<br/>High-Throughput Nucleotide Sequencing--statistics & numerical data<br/>Humans<br/>Lymphocytes--cytology<br/>Osteoblasts--cytology<br/>RNA, Guide, CRISPR-Cas Systems--genetics