TY  - GEN
AU  - Liao,Qiwen
AU  - Li,Shengnan
AU  - Siu,Shirley Weng In
AU  - Morlighem,Jean-Étienne R L
AU  - Wong,Clarence Tsun Ting
AU  - Wang,Xiufen
AU  - Rádis-Baptista,Gandhi
AU  - Lee,Simon Ming-Yuen
TI  - Novel neurotoxic peptides from Protopalythoa variabilis virtually interact with voltage-gated sodium channel and display anti-epilepsy and neuroprotective activities in zebrafish
SN  - 1432-0738
PY  - 2020///0304
KW  - Amino Acid Sequence
KW  - Animals
KW  - Anthozoa
KW  - chemistry
KW  - Anticonvulsants
KW  - pharmacology
KW  - Heme Oxygenase (Decyclizing)
KW  - metabolism
KW  - Locomotion
KW  - Molecular Docking Simulation
KW  - Molecular Dynamics Simulation
KW  - Neuroprotective Agents
KW  - Nitric Oxide Synthase Type II
KW  - Oxidopamine
KW  - adverse effects
KW  - PC12 Cells
KW  - Pentylenetetrazole
KW  - Peptides
KW  - chemical synthesis
KW  - Protein Structure, Tertiary
KW  - Rats
KW  - Reactive Oxygen Species
KW  - Voltage-Gated Sodium Channel Blockers
KW  - Voltage-Gated Sodium Channels
KW  - Zebrafish
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1007/s00204-018-2334-5
ER  -