Liao, Qiwen <br/><br/>
Novel neurotoxic peptides from Protopalythoa variabilis virtually interact with voltage-gated sodium channel and display anti-epilepsy and neuroprotective activities in zebrafish.  [electronic resource] 

 -  Archives of toxicology  01 2019 
 - 189-206 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1432-0738 
<br/><br/><label>Standard No.: </label>10.1007/s00204-018-2334-5  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acid Sequence<br/>Animals<br/>Anthozoa--chemistry<br/>Anticonvulsants--pharmacology<br/>Heme Oxygenase (Decyclizing)--metabolism<br/>Locomotion<br/>Molecular Docking Simulation<br/>Molecular Dynamics Simulation<br/>Neuroprotective Agents--pharmacology<br/>Nitric Oxide Synthase Type II--metabolism<br/>Oxidopamine--adverse effects<br/>PC12 Cells<br/>Pentylenetetrazole--adverse effects<br/>Peptides--chemical synthesis<br/>Protein Structure, Tertiary<br/>Rats<br/>Reactive Oxygen Species--metabolism<br/>Voltage-Gated Sodium Channel Blockers--pharmacology<br/>Voltage-Gated Sodium Channels--metabolism<br/>Zebrafish