TY - GEN AU - Iyer,Dharini AU - Zhao,Quanyi AU - Wirka,Robert AU - Naravane,Ameay AU - Nguyen,Trieu AU - Liu,Boxiang AU - Nagao,Manabu AU - Cheng,Paul AU - Miller,Clint L AU - Kim,Juyong Brian AU - Pjanic,Milos AU - Quertermous,Thomas TI - Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk SN - 1553-7404 PY - 2019///0215 KW - Basic Helix-Loop-Helix Transcription Factors KW - genetics KW - Binding Sites KW - Cell Differentiation KW - Coronary Artery Disease KW - Epistasis, Genetic KW - Genetic Predisposition to Disease KW - Genome-Wide Association Study KW - Humans KW - Muscle, Smooth, Vascular KW - metabolism KW - Polymorphism, Single Nucleotide KW - Primary Cell Culture KW - Signal Transduction KW - Smad3 Protein KW - Transforming Growth Factor beta N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1371/journal.pgen.1007681 ER -