TY  - GEN
AU  - Eustace,Alex J
AU  - Conlon,Neil T
AU  - McDermott,Martina S J
AU  - Browne,Brigid C
AU  - O'Leary,Patrick
AU  - Holmes,Frankie A
AU  - Espina,Virginia
AU  - Liotta,Lance A
AU  - O'Shaughnessy,Joyce
AU  - Gallagher,Clair
AU  - O'Driscoll,Lorraine
AU  - Rani,Sweta
AU  - Madden,Stephen F
AU  - O'Brien,Neil A
AU  - Ginther,Charles
AU  - Slamon,Dennis
AU  - Walsh,Naomi
AU  - Gallagher,William M
AU  - Zagozdzon,Radoslaw
AU  - Watson,William R
AU  - O'Donovan,Norma
AU  - Crown,John
TI  - Development of acquired resistance to lapatinib may sensitise HER2-positive breast cancer cells to apoptosis induction by obatoclax and TRAIL
SN  - 1471-2407
PY  - 2019///0114
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Apoptosis
KW  - drug effects
KW  - Breast Neoplasms
KW  - drug therapy
KW  - CASP8 and FADD-Like Apoptosis Regulating Protein
KW  - metabolism
KW  - Cell Line, Tumor
KW  - Drug Resistance, Neoplasm
KW  - genetics
KW  - Female
KW  - Forkhead Box Protein O3
KW  - biosynthesis
KW  - Gene Expression
KW  - Genes, erbB-2
KW  - Humans
KW  - Lapatinib
KW  - Phosphorylation
KW  - Proto-Oncogene Proteins c-bcl-2
KW  - TNF-Related Apoptosis-Inducing Ligand
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1186/s12885-018-4852-1
ER  -