TY - GEN AU - Domínguez-Andrés,Jorge AU - Novakovic,Boris AU - Li,Yang AU - Scicluna,Brendon P AU - Gresnigt,Mark S AU - Arts,Rob J W AU - Oosting,Marije AU - Moorlag,Simone J C F M AU - Groh,Laszlo A AU - Zwaag,Jelle AU - Koch,Rebecca M AU - Ter Horst,Rob AU - Joosten,Leo A B AU - Wijmenga,Cisca AU - Michelucci,Alessandro AU - van der Poll,Tom AU - Kox,Matthijs AU - Pickkers,Peter AU - Kumar,Vinod AU - Stunnenberg,Henk AU - Netea,Mihai G TI - The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity SN - 1932-7420 PY - 2020///0224 KW - Adolescent KW - Adult KW - Animals KW - Carboxy-Lyases KW - metabolism KW - Endotoxemia KW - chemically induced KW - Escherichia coli Infections KW - immunology KW - Healthy Volunteers KW - Humans KW - Immune Tolerance KW - Immunity, Innate KW - Lipopolysaccharides KW - Male KW - Mice KW - Monocytes KW - cytology KW - RAW 264.7 Cells KW - Succinate Dehydrogenase KW - Succinates KW - Young Adult N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.cmet.2018.09.003 ER -