TY - GEN AU - Yu,Wenlei AU - Li,Liang AU - Wang,Guangming AU - Zhang,Wenjun AU - Xu,Jun AU - Liang,Aibin TI - KU70 Inhibition Impairs Both Non-Homologous End Joining and Homologous Recombination DNA Damage Repair Through SHP-1 Induced Dephosphorylation of SIRT1 in T-Cell Acute Lymphoblastic Leukemia (T-ALL) [corrected] SN - 1421-9778 PY - 2018///1023 KW - Animals KW - Apoptosis KW - Ataxia Telangiectasia Mutated Proteins KW - metabolism KW - Cell Cycle Checkpoints KW - DNA Breaks, Double-Stranded KW - DNA End-Joining Repair KW - Humans KW - Jurkat Cells KW - Ku Autoantigen KW - antagonists & inhibitors KW - Leukemia-Lymphoma, Adult T-Cell KW - drug therapy KW - Mice KW - Mice, Inbred NOD KW - Mice, SCID KW - Phosphorylation KW - Protein Tyrosine Phosphatase, Non-Receptor Type 6 KW - RNA Interference KW - RNA, Small Interfering KW - Rad51 Recombinase KW - Recombinational DNA Repair KW - Sirtuin 1 N1 - Publication Type: Journal Article UR - https://doi.org/10.1159/000493815 ER -