TY - GEN AU - Zhu,Jun-Rong AU - Lu,Hai-Dan AU - Guo,Chao AU - Fang,Wei-Rong AU - Zhao,Hong-Dong AU - Zhou,Jun-Shan AU - Wang,Feng AU - Zhao,Yan-Li AU - Li,Yun-Man AU - Zhang,Ying-Dong AU - Yang,Chang-Qing AU - Sun,Jian-Guo TI - Berberine attenuates ischemia-reperfusion injury through inhibiting HMGB1 release and NF-κB nuclear translocation SN - 1745-7254 PY - 2019///0115 KW - Animals KW - Berberine KW - therapeutic use KW - Brain KW - pathology KW - Brain Edema KW - drug therapy KW - Down-Regulation KW - Glycyrrhizic Acid KW - HMGB1 Protein KW - antagonists & inhibitors KW - Infarction, Middle Cerebral Artery KW - Interleukin-1beta KW - metabolism KW - Interleukin-6 KW - Male KW - Mice, Inbred C57BL KW - NF-kappa B p50 Subunit KW - Neuroprotective Agents KW - Reperfusion Injury KW - complications KW - Signal Transduction KW - drug effects KW - Toll-Like Receptor 4 KW - genetics KW - Tumor Necrosis Factor-alpha N1 - Publication Type: Journal Article UR - https://doi.org/10.1038/s41401-018-0160-1 ER -