TY - GEN AU - Wang,Wenyu AU - Oguz,Gokce AU - Lee,Puay Leng AU - Bao,Yi AU - Wang,Panpan AU - Terp,Mikkel Green AU - Ditzel,Henrik J AU - Yu,Qiang TI - KDM4B-regulated unfolded protein response as a therapeutic vulnerability in SN - 1540-9538 PY - 2019///0904 KW - Animals KW - Apoptosis KW - drug effects KW - Cell Line, Tumor KW - Drug Resistance, Neoplasm KW - Enzyme Inhibitors KW - pharmacology KW - Eukaryotic Initiation Factor-2 KW - genetics KW - Female KW - Humans KW - Jumonji Domain-Containing Histone Demethylases KW - Mice KW - Mice, Inbred NOD KW - Mice, SCID KW - PTEN Phosphohydrolase KW - deficiency KW - Phosphatidylinositol 3-Kinases KW - Phosphoinositide-3 Kinase Inhibitors KW - Proto-Oncogene Proteins c-akt KW - antagonists & inhibitors KW - Signal Transduction KW - Triple Negative Breast Neoplasms KW - drug therapy KW - Unfolded Protein Response KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1084/jem.20180439 ER -