Huang, Chih-Yang
HMGB1 promotes ERK-mediated mitochondrial Drp1 phosphorylation for chemoresistance through RAGE in colorectal cancer. [electronic resource]
- Cell death & disease 09 2018
- 1004 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
ISSN: 2041-4889
Standard No.: 10.1038/s41419-018-1019-6 doi
Subjects--Topical Terms: Animals Antigens, Neoplasm--genetics Antineoplastic Agents--pharmacology Apoptosis--drug effects Autophagy--drug effects Cell Line, Tumor Colorectal Neoplasms--drug therapy Disease-Free Survival Drug Resistance, Neoplasm--genetics Dynamins GTP Phosphohydrolases--genetics HMGB1 Protein--genetics Humans MAP Kinase Signaling System--drug effects Mice Mice, Inbred BALB C Mice, Nude Microtubule-Associated Proteins--genetics Mitochondria--drug effects Mitochondrial Dynamics--drug effects Mitochondrial Proteins--genetics Mitogen-Activated Protein Kinases--genetics Phosphorylation--drug effects RNA Interference--drug effects Rectal Neoplasms--drug therapy Tumor Microenvironment--drug effects