Nangia, Varuna <br/><br/>
Exploiting MCL1 Dependency with Combination MEK + MCL1 Inhibitors Leads to Induction of Apoptosis and Tumor Regression in   [electronic resource] 

 -  Cancer discovery  12 2018 
 - 1598-1613 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>2159-8290 
<br/><br/><label>Standard No.: </label>10.1158/2159-8290.CD-18-0277  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>A549 Cells<br/>Aniline Compounds--administration & dosage<br/>Animals<br/>Antineoplastic Agents--administration & dosage<br/>Antineoplastic Combined Chemotherapy Protocols--pharmacology<br/>Apoptosis--drug effects<br/>Benzamides--pharmacology<br/>Carcinoma, Non-Small-Cell Lung--drug therapy<br/>Cell Line, Tumor<br/>Diphenylamine--analogs & derivatives<br/>Humans<br/>Lung Neoplasms--drug therapy<br/>Mice, Knockout<br/>Mice, Nude<br/>Mice, SCID<br/>Mitogen-Activated Protein Kinase Kinases--antagonists & inhibitors<br/>Myeloid Cell Leukemia Sequence 1 Protein--antagonists & inhibitors<br/>Protein Kinase Inhibitors--administration & dosage<br/>Proto-Oncogene Proteins p21(ras)--antagonists & inhibitors<br/>Sulfonamides--administration & dosage<br/>Tumor Burden--drug effects<br/>Xenograft Model Antitumor Assays--methods