Guo, Ming <br/><br/>
Dual potent ALK and ROS1 inhibitors combating drug-resistant mutants: Synthesis and biological evaluation of aminopyridine-containing diarylaminopyrimidine derivatives.  [electronic resource] 

 -  European journal of medicinal chemistry  Oct 2018 
 - 322-333 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1768-3254 
<br/><br/><label>Standard No.: </label>10.1016/j.ejmech.2018.09.012  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aminopyridines--chemistry<br/>Anaplastic Lymphoma Kinase<br/>Antineoplastic Agents--chemistry<br/>Apoptosis--drug effects<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Drug Resistance, Neoplasm<br/>Humans<br/>Neoplasms--drug therapy<br/>Point Mutation<br/>Protein Kinase Inhibitors--chemistry<br/>Protein-Tyrosine Kinases--antagonists & inhibitors<br/>Proto-Oncogene Proteins--antagonists & inhibitors<br/>Receptor Protein-Tyrosine Kinases--antagonists & inhibitors