Gicquel, Maxime <br/><br/>
Inhibition of p53-Murine Double Minute 2 (MDM2) Interactions with 3,3'-Spirocyclopentene Oxindole Derivatives.  [electronic resource] 

 -  Journal of medicinal chemistry  10 2018 
 - 9386-9392 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/acs.jmedchem.8b01137  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--chemistry<br/>Cell Proliferation--drug effects<br/>Drug Design<br/>HCT116 Cells<br/>Humans<br/>Models, Molecular<br/>Molecular Conformation<br/>Oxindoles--chemistry<br/>Protein Binding--drug effects<br/>Proto-Oncogene Proteins c-mdm2--metabolism<br/>Spiro Compounds--chemistry<br/>Structure-Activity Relationship<br/>Tumor Suppressor Protein p53--metabolism