Verlekar, Dattesh

Ceramide synthase-6 confers resistance to chemotherapy by binding to CD95/Fas in T-cell acute lymphoblastic leukemia. [electronic resource] - Cell death & disease 09 2018 - 925 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

2041-4889

10.1038/s41419-018-0964-4 doi


Apoptosis--physiology
Biphenyl Compounds--pharmacology
Caspase 8--metabolism
Caspase Inhibitors--pharmacology
Cell Line
Cell Line, Tumor
Ceramides--metabolism
Drug Resistance, Neoplasm--physiology
HEK293 Cells
Humans
Membrane Proteins--genetics
Nitrophenols--pharmacology
Oligopeptides--pharmacology
Piperazines--pharmacology
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma--drug therapy
Protein Binding
Proto-Oncogene Proteins c-bcl-2--antagonists & inhibitors
RNA Interference
RNA, Small Interfering--genetics
Sphingolipids--metabolism
Sphingosine N-Acyltransferase--genetics
Sulfonamides--pharmacology
fas Receptor--metabolism