TY  - GEN
AU  - Benej,Martin
AU  - Hong,Xiangqian
AU  - Vibhute,Sandip
AU  - Scott,Sabina
AU  - Wu,Jinghai
AU  - Graves,Edward
AU  - Le,Quynh-Thu
AU  - Koong,Albert C
AU  - Giaccia,Amato J
AU  - Yu,Bing
AU  - Chen,Ching-Shih
AU  - Papandreou,Ioanna
AU  - Denko,Nicholas C
TI  - Papaverine and its derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism
SN  - 1091-6490
PY  - 2018///1214
KW  - Animals
KW  - CRISPR-Cas Systems
KW  - Cell Hypoxia
KW  - drug effects
KW  - Cell Proliferation
KW  - Electron Transport Complex I
KW  - Female
KW  - Humans
KW  - Lung Neoplasms
KW  - drug therapy
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mitochondria
KW  - NADH Dehydrogenase
KW  - antagonists & inhibitors
KW  - Oxygen
KW  - metabolism
KW  - Papaverine
KW  - pharmacology
KW  - Phosphodiesterase Inhibitors
KW  - Radiation Tolerance
KW  - Radiation-Sensitizing Agents
KW  - Tumor Cells, Cultured
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1073/pnas.1808945115
ER  -