TY - GEN AU - Kurmi,Kiran AU - Hitosugi,Sadae AU - Yu,Jia AU - Boakye-Agyeman,Felix AU - Wiese,Elizabeth K AU - Larson,Thomas R AU - Dai,Qing AU - Machida,Yuichi J AU - Lou,Zhenkun AU - Wang,Liewei AU - Boughey,Judy C AU - Kaufmann,Scott H AU - Goetz,Matthew P AU - Karnitz,Larry M AU - Hitosugi,Taro TI - Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway SN - 1932-7420 PY - 2019///1022 KW - Animals KW - Antineoplastic Agents KW - therapeutic use KW - Antineoplastic Combined Chemotherapy Protocols KW - Breast Neoplasms KW - metabolism KW - Cell Line, Tumor KW - Cell Transformation, Neoplastic KW - Creatine Kinase KW - genetics KW - Creatinine KW - analogs & derivatives KW - Drug Resistance, Neoplasm KW - Energy Metabolism KW - Energy Transfer KW - Female KW - Gene Knockdown Techniques KW - Humans KW - Lapatinib KW - Mice KW - Mice, Nude KW - Mitochondria KW - Mitochondrial Proteins KW - Phosphocreatine KW - Phosphorylation KW - Receptor, ErbB-2 KW - Trastuzumab KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.cmet.2018.08.008 ER -